mPEG-Acetic Acid

mPEGn-OCH₂COOH is primarily used for bioconjugation with amines via EDC/sulfo-NHS chemistry, enabling PEGylation of proteins, peptides, and nanoparticles to enhance solubility and reduce immunogenicity. Its key advantages include terminal carboxylic acid group reactivity, tunable PEG length (n), and improved pharmacokinetics, though pH-sensitive conjugation conditions require optimization.